Pub. Date : 2001 Oct 31
PMID : 11690641
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells. | Phytanic Acid | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 2 | Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells. | Docosahexaenoic Acids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 3 | However, in combination with retinoic acid receptor (RAR)-ligands (all-trans-RA or synthetic Am580) phytanic acid enhanced the induction of CYP26 and RA-metabolism in comparison to treatments with all-trans-RA or Am580 alone. | Phytanic Acid | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 4 | Also treatment with DHA did not affect CYP26 gene expression and RA-metabolism but cotreatment of the cells with DHA and all-trans-RA or Am580 enhanced the induction of CYP26, in comparison to the induction caused by all-trans-RA or Am580 alone. | Docosahexaenoic Acids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 5 | This study indicates that food compounds such as phytanic acid and DHA that are RXR-agonists and have an impact on intestinal CYP26 gene expression and metabolism of all-trans-RA in intestinal cells. | Phytanic Acid | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 6 | This study indicates that food compounds such as phytanic acid and DHA that are RXR-agonists and have an impact on intestinal CYP26 gene expression and metabolism of all-trans-RA in intestinal cells. | Docosahexaenoic Acids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 7 | This study indicates that food compounds such as phytanic acid and DHA that are RXR-agonists and have an impact on intestinal CYP26 gene expression and metabolism of all-trans-RA in intestinal cells. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |