Pub. Date : 2001 Nov
PMID : 11602523
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor. | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 2 | Taken together, these data demonstrate a pivotal role for PXR in the regulation of drug-induced hepatomegaly and in the metabolism (CYP3A), transport (Oatp2), biosynthesis (Cyp7a1), and excretion of xenobiotics and bile acids in vivo. | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |