Pub. Date : 2001 Oct
PMID : 11561067
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro, SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, IC50 = 3.7 nM, and rat neutrophil chemotaxis in a concentration-dependent manner, IC50 = 70 nM. | 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 2 | In vitro, SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, IC50 = 3.7 nM, and rat neutrophil chemotaxis in a concentration-dependent manner, IC50 = 70 nM. | 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 3 | In vitro, SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, IC50 = 3.7 nM, and rat neutrophil chemotaxis in a concentration-dependent manner, IC50 = 70 nM. | Calcium | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 4 | In vitro, SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, IC50 = 3.7 nM, and rat neutrophil chemotaxis in a concentration-dependent manner, IC50 = 70 nM. | Calcium | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 5 | SB-265610 reduced the antiapoptotic effect of CINC-1 to the levels of those untreated with CINC-1. | 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 6 | SB-265610 reduced the antiapoptotic effect of CINC-1 to the levels of those untreated with CINC-1. | 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea | C-X-C motif chemokine ligand 1 | Rattus norvegicus |