Title : SHV-16, a beta-lactamase with a pentapeptide duplication in the omega loop.

Pub. Date : 2001 Sep

PMID : 11502518






1 Functional Relationships(s)
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1 A clinical isolate of Klebsiella pneumoniae was found to be resistant to ampicillin (MIC of 128 microg/ml), ticarcillin (MIC of 512 microg/ml), and ceftazidime (MIC of 128 microg/ml) and susceptible to all other beta-lactams; a synergistic effect between clavulanate and ceftazidime suggested the presence of an extended-spectrum beta-lactamase (ESBL). Ceftazidime EsbL Escherichia coli