Title : Connective tissue growth factor and its regulation: a new element in diabetic glomerulosclerosis.

Pub. Date : 2001 May-Jul

PMID : 11499561






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 However, exposure to TGF-beta, increased glucose concentrations, or cyclic mechanical strain, all causal factors in glomerulosclerosis, markedly induced the expression of CTGF transcripts. Glucose cellular communication network factor 2 Mus musculus
2 The induction of CTGF protein by a high glucose concentration was mediated by TGF-beta, since a TGF-beta neutralizing antibody blocked this stimulation. Glucose cellular communication network factor 2 Mus musculus