Pub. Date : 2001 Jul 27
PMID : 11467847
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Transcriptional activation of the nuclear receptor corepressor RIP140 by retinoic acid: a potential negative-feedback regulatory mechanism. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
2 | Through the use of microarray analysis it was discovered that the nuclear receptor coregulator, receptor interacting protein 140 (RIP140), was induced early during all-trans retinoic acid (RA)-induced differentiation of human embryonal carcinoma cells. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
3 | Through the use of microarray analysis it was discovered that the nuclear receptor coregulator, receptor interacting protein 140 (RIP140), was induced early during all-trans retinoic acid (RA)-induced differentiation of human embryonal carcinoma cells. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
4 | Through the use of microarray analysis it was discovered that the nuclear receptor coregulator, receptor interacting protein 140 (RIP140), was induced early during all-trans retinoic acid (RA)-induced differentiation of human embryonal carcinoma cells. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
5 | Through the use of microarray analysis it was discovered that the nuclear receptor coregulator, receptor interacting protein 140 (RIP140), was induced early during all-trans retinoic acid (RA)-induced differentiation of human embryonal carcinoma cells. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
6 | A rapid, fourfold induction of RIP140 mRNA was detected within 3 h of RA treatment in human embryonal carcinoma and MCF-7 human breast cancer cells. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
7 | RIP140 protein levels were induced within 6 h of RA treatment. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |
8 | These data are consistent with a model by which RA induction of RIP140 supplies a negative feedback signal toward ligand-activated retinoid receptors. | Tretinoin | nuclear receptor interacting protein 1 | Homo sapiens |