Title : Cloning, expression, signaling mechanisms, and membrane targeting of P2Y(11) receptors in Madin Darby canine kidney cells.

Pub. Date : 2001 Jul

PMID : 11408597






1 Functional Relationships(s)
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1 BL addition of 200 microM ADP beta S to confluent monolayers of MDCK-D1 cells produces an increase in short circuit current (I(sc)) (11.6 +/- 1.6 microA/cm(2)) whereas apical addition of agonist has no effect, confirming targeting of functional endogenous P2Y(11) receptors to the BL surface. adenosine 5'-O-(2-thiodiphosphate) purinergic receptor P2Y11 Homo sapiens