Title : Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes.

Pub. Date : 2001 Jan 30

PMID : 11170435






2 Functional Relationships(s)
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Protein Name
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1 hsp90 and hsp70 are essential components of a five-protein system, including also the nonessential cochaperones Hop, hsp40, and p23, that assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of the steroid binding pocket to access by steroid. Steroids DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 Homo sapiens
2 hsp90 and hsp70 are essential components of a five-protein system, including also the nonessential cochaperones Hop, hsp40, and p23, that assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of the steroid binding pocket to access by steroid. Steroids DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 Homo sapiens