Title : Effect of dexamethasone on insulin-like growth factor-1 expression in a rabbit model of growth retardation.

Pub. Date : 2000 Jun

PMID : 10873033






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1 Effect of dexamethasone on insulin-like growth factor-1 expression in a rabbit model of growth retardation. Dexamethasone insulin-like growth factor I Oryctolagus cuniculus
2 To determine if fetal insulin-like growth factor-1 (IGF-1) expression is altered in response to maternal dexamethasone administration, this rabbit model of intrauterine growth retardation (IUGR) was utilized. Dexamethasone insulin-like growth factor I Oryctolagus cuniculus
3 To determine if fetal insulin-like growth factor-1 (IGF-1) expression is altered in response to maternal dexamethasone administration, this rabbit model of intrauterine growth retardation (IUGR) was utilized. Dexamethasone insulin-like growth factor I Oryctolagus cuniculus
4 CONCLUSIONS: This report provides the first description of maternal steroid administration effecting a marked increase in fetal IGF-1 mRNA expression and IGF-1 protein levels in an in vivo rabbit model of IUGR. Steroids insulin-like growth factor I Oryctolagus cuniculus
5 CONCLUSIONS: This report provides the first description of maternal steroid administration effecting a marked increase in fetal IGF-1 mRNA expression and IGF-1 protein levels in an in vivo rabbit model of IUGR. Steroids insulin-like growth factor I Oryctolagus cuniculus