Title : Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells.

Pub. Date : 2000 Apr

PMID : 10737604






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Overexpression of PPT1 inhibited this C2-ceramide- or LY294002-mediated activation of caspase-3 by 50%. N-acetylsphingosine palmitoyl-protein thioesterase 1 Homo sapiens
2 Overexpression of PPT1 inhibited this C2-ceramide- or LY294002-mediated activation of caspase-3 by 50%. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one palmitoyl-protein thioesterase 1 Homo sapiens
3 The C2-ceramide-induced membrane association of p21Ras was reduced by 30-50% in PPT1-overexpressing cells compared with control. N-acetylsphingosine palmitoyl-protein thioesterase 1 Homo sapiens