Title : Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5' flanking region.

Pub. Date : 2000 Jan 25

PMID : 10721715






8 Functional Relationships(s)
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1 Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5" flanking region. triplex-forming oligonucleotide hemoglobin subunit gamma 1 Homo sapiens
2 Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5" flanking region. triplex-forming oligonucleotide hemoglobin subunit gamma 1 Homo sapiens
3 Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5" flanking region. tfo hemoglobin subunit gamma 1 Homo sapiens
4 Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5" flanking region. tfo hemoglobin subunit gamma 1 Homo sapiens
5 We have explored the possibility of activating the gamma-globin gene expression by triplex-forming oligonucleotide (TFO)-directed targeted mutagenesis. triplex-forming oligonucleotide hemoglobin subunit gamma 1 Homo sapiens
6 We have explored the possibility of activating the gamma-globin gene expression by triplex-forming oligonucleotide (TFO)-directed targeted mutagenesis. tfo hemoglobin subunit gamma 1 Homo sapiens
7 Using a psoralen-conjugated TFO designed to bind to a site overlapping with an Oct-1 binding site at the -280 region of the gamma-globin gene, targeted mutagenesis of the Oct-1 binding site has been achieved by transfecting the in-vitro-formed plasmid-oligo complex into human normal fibroblast (NF) cells. Ficusin hemoglobin subunit gamma 1 Homo sapiens
8 Using a psoralen-conjugated TFO designed to bind to a site overlapping with an Oct-1 binding site at the -280 region of the gamma-globin gene, targeted mutagenesis of the Oct-1 binding site has been achieved by transfecting the in-vitro-formed plasmid-oligo complex into human normal fibroblast (NF) cells. tfo hemoglobin subunit gamma 1 Homo sapiens