Title : Evidence for regulation of NF-kappaB by poly(ADP-ribose) polymerase.

Pub. Date : 2000 Mar 15

PMID : 10698690






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Further analysis with purified recombinant NF-kappaB proteins revealed that both rp50 and rMBP-p65 (Rel A) proteins, but not rGST-IkappaB, could be poly(ADP-ribosyl)ated in vitro and that the modification resulted in a marked decrease in the DNA-binding activity of rMBP-p65, whereas a slight activation was observed in rp50. rmbp v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus
2 Further analysis with purified recombinant NF-kappaB proteins revealed that both rp50 and rMBP-p65 (Rel A) proteins, but not rGST-IkappaB, could be poly(ADP-ribosyl)ated in vitro and that the modification resulted in a marked decrease in the DNA-binding activity of rMBP-p65, whereas a slight activation was observed in rp50. rmbp v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus
3 Further analysis with purified recombinant NF-kappaB proteins revealed that both rp50 and rMBP-p65 (Rel A) proteins, but not rGST-IkappaB, could be poly(ADP-ribosyl)ated in vitro and that the modification resulted in a marked decrease in the DNA-binding activity of rMBP-p65, whereas a slight activation was observed in rp50. rmbp v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus
4 Poly(ADP-ribosyl)ated p65/NF-kappaB was detected in the cytosol of wild type L1210 cells by immunoblotting with anti-poly(ADP-ribose) and anti-p65 antibodies. poly(adp-ribosyl)ated v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus
5 Poly(ADP-ribosyl)ated p65/NF-kappaB was detected in the cytosol of wild type L1210 cells by immunoblotting with anti-poly(ADP-ribose) and anti-p65 antibodies. poly(adp-ribosyl)ated v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus