Pub. Date : 2000 Feb
PMID : 10686424
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deletion of cysteine 369 in lysyl hydroxylase 1 eliminates enzyme activity and causes Ehlers-Danlos syndrome type VI. | Cysteine | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Homo sapiens |
| 2 | This study describes the relative contribution of the 10 cysteine residues in lysyl hydroxylase 1 (LH1) to enzyme activity. | Cysteine | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Homo sapiens |
| 3 | This study describes the relative contribution of the 10 cysteine residues in lysyl hydroxylase 1 (LH1) to enzyme activity. | Cysteine | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Homo sapiens |
| 4 | We confirmed that the loss of cysteine 369 in the deleted sequence contributed to the diminished enzyme activity by structure/function analysis of mutant LH1 constructs, in which C369 and the nine other cysteines were individually mutated to serine by site-directed mutagenesis of a normal pAcGP67/LH1cDNA construct. | Cysteine | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Homo sapiens |