Pub. Date : 1999 Dec 15
PMID : 10585861
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The experiments described in this paper were designed to determine the mechanism underlying the increase in 8-isoprostaglandin F(2alpha) (8-epi-PGF(2alpha)) production by cultured human endothelial cells during reoxygenation following hypoxia. | 8-isoprostaglandin f | placental growth factor | Homo sapiens |
| 2 | The production of 8-epi-PGF(2alpha) was also inhibited by indomethacin and aspirin. | Indomethacin | placental growth factor | Homo sapiens |
| 3 | The production of 8-epi-PGF(2alpha) was also inhibited by indomethacin and aspirin. | Aspirin | placental growth factor | Homo sapiens |
| 4 | Exogenous hydrogen peroxide stimulated 8-epi-PGF(2alpha) production by normoxic cells, and aspirin inhibited the hydrogen peroxide-mediated increase in 8-epi-PGF(2alpha) production. | Hydrogen Peroxide | placental growth factor | Homo sapiens |
| 5 | Exogenous hydrogen peroxide stimulated 8-epi-PGF(2alpha) production by normoxic cells, and aspirin inhibited the hydrogen peroxide-mediated increase in 8-epi-PGF(2alpha) production. | Hydrogen Peroxide | placental growth factor | Homo sapiens |
| 6 | Exogenous hydrogen peroxide stimulated 8-epi-PGF(2alpha) production by normoxic cells, and aspirin inhibited the hydrogen peroxide-mediated increase in 8-epi-PGF(2alpha) production. | Aspirin | placental growth factor | Homo sapiens |
| 7 | Exogenous hydrogen peroxide stimulated 8-epi-PGF(2alpha) production by normoxic cells, and aspirin inhibited the hydrogen peroxide-mediated increase in 8-epi-PGF(2alpha) production. | Hydrogen Peroxide | placental growth factor | Homo sapiens |
| 8 | These results indicate that the reactive oxygen species responsible for 8-epi-PGF(2alpha) synthesis during reoxygenation is hydrogen peroxide and that in endothelial cells 8-epi-PGF(2alpha) synthesis is mediated by prostaglandin H(2) synthase (PGHS). | Reactive Oxygen Species | placental growth factor | Homo sapiens |
| 9 | These results indicate that the reactive oxygen species responsible for 8-epi-PGF(2alpha) synthesis during reoxygenation is hydrogen peroxide and that in endothelial cells 8-epi-PGF(2alpha) synthesis is mediated by prostaglandin H(2) synthase (PGHS). | Hydrogen Peroxide | placental growth factor | Homo sapiens |
| 10 | In the presence of exogenous arachidonic acid the COS-7 cells expressing human PGHS-1 produced substantial amounts of PGE(2) and 8-epi-PGF(2alpha). | Arachidonic Acid | placental growth factor | Homo sapiens |
| 11 | In the presence of exogenous arachidonic acid the COS-7 cells expressing human PGHS-1 produced substantial amounts of PGE(2) and 8-epi-PGF(2alpha). | carbonyl sulfide | placental growth factor | Homo sapiens |