Pub. Date : 1999 Jun
PMID : 10466117
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: The purpose of this study was to determine whether exogenous nitric oxide could block permeability alterations induced by neutrophil-independent (histamine) and neutrophil-dependent (CINC/gro) inflammatory mediators. | Nitric Oxide | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 2 | CONCLUSIONS: This study demonstrates that exogenous nitric oxide and 8-Br-cGMP could block adhesion dependent alterations in vascular permeability induced by CINC/gro, while adhesion-independent alterations in permeability induced by histamine could be blocked by exogenous NO but not 8-Br-cGMP. | Nitric Oxide | C-X-C motif chemokine ligand 1 | Rattus norvegicus |
| 3 | CONCLUSIONS: This study demonstrates that exogenous nitric oxide and 8-Br-cGMP could block adhesion dependent alterations in vascular permeability induced by CINC/gro, while adhesion-independent alterations in permeability induced by histamine could be blocked by exogenous NO but not 8-Br-cGMP. | 8-bromoguanosino-3',5'-cyclic monophosphorothioate | C-X-C motif chemokine ligand 1 | Rattus norvegicus |