Title : Inhibition of interleukin-1-induced proteoglycan degradation and nitric oxide production in bovine articular cartilage/chondrocyte cultures by the natural product, hymenialdisine.

Pub. Date : 1999 Aug

PMID : 10411566






1 Functional Relationships(s)
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1 The effect on iNOS gene expression was determined by Northern blot analysis in chondrocytes grown in monolayer, and inhibition by hymenialdisine was observed with an IC(50) of approximately 0.8 microM. hymenialdisine nitric oxide synthase 2 Bos taurus