Title : The effect of phospholipase A2 inhibitors on proliferation and apoptosis of murine intestinal cells.

Pub. Date : 1999 Jun 1

PMID : 10334889






3 Functional Relationships(s)
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1 BACKGROUND: Group II phospholipase A2 (PLA2) enzymes, the rate controlling enzymes in arachidonic acid metabolism, have been well characterized and subdivided into secretory 14-kDa PLA2 (sPLA2) and cytoplasmic 85-kDa PLA2 (cPLA2). Arachidonic Acid phospholipase A2 group IIA Rattus norvegicus
2 The sPLA2 inhibitor, but not the cPLA2 inhibitor, significantly inhibited [3H]thymidine incorporation in the malignant cell line. Tritium phospholipase A2 group IIA Rattus norvegicus
3 The sPLA2 inhibitor, but not the cPLA2 inhibitor, significantly inhibited [3H]thymidine incorporation in the malignant cell line. Thymidine phospholipase A2 group IIA Rattus norvegicus