Pub. Date : 1999 Jun 1
PMID : 10333487
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mammalian thioredoxin reductase (TR) is a flavoprotein catalysing reduction of oxidized thioredoxin in an NADPH-dependent manner, and contains a selenocysteine (Sec) residue near the C-terminus. | NADP | peroxiredoxin 5 | Rattus norvegicus |
| 2 | Mammalian thioredoxin reductase (TR) is a flavoprotein catalysing reduction of oxidized thioredoxin in an NADPH-dependent manner, and contains a selenocysteine (Sec) residue near the C-terminus. | NADP | peroxiredoxin 5 | Rattus norvegicus |
| 3 | We observed that TR activity was decreased in A549 cells by the lowering of the fetal bovine serum content in the culture medium and was recovered by the addition of selenium. | Selenium | peroxiredoxin 5 | Rattus norvegicus |
| 4 | TR activities in COS-1 cells expressing rat TR were increased in accordance with supplemented sodium selenite concentrations, whereas levels of TR protein, examined by Western blotting, were not affected by sodium selenite concentrations. | Sodium Selenite | peroxiredoxin 5 | Rattus norvegicus |
| 5 | TR activities in COS-1 cells expressing rat TR were increased in accordance with supplemented sodium selenite concentrations, whereas levels of TR protein, examined by Western blotting, were not affected by sodium selenite concentrations. | Sodium Selenite | peroxiredoxin 5 | Rattus norvegicus |
| 6 | These data clearly showed a requirement of selenium for the formation of functional TR protein. | Selenium | peroxiredoxin 5 | Rattus norvegicus |