Pub. Date : 1999 Mar 5
PMID : 10037702
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Spermidine/spermine N1-acetyltransferase (SSAT) appears to be the rate-limiting enzyme of polyamine catabolism, yet studies of its regulation have been limited by the low amounts of SSAT in uninduced cells. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 2 | Spermidine/spermine N1-acetyltransferase (SSAT) appears to be the rate-limiting enzyme of polyamine catabolism, yet studies of its regulation have been limited by the low amounts of SSAT in uninduced cells. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 3 | The increased SSAT activity caused perturbations in polyamine homeostasis and led to a reduction in the rate of growth under clonal conditions. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 4 | N1,N12-bis(ethyl)spermine greatly increased SSAT activity in controls and SSAT transfected clones (to about 10 and 60 nmol/min/mg protein, respectively). | N(1), N(12)-diethylspermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 5 | N1,N12-bis(ethyl)spermine greatly increased SSAT activity in controls and SSAT transfected clones (to about 10 and 60 nmol/min/mg protein, respectively). | N(1), N(12)-diethylspermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 6 | N1, N12-Bis(ethyl)spermine caused an increase in the SSAT half-life and a slight increase in SSAT mRNA, but these changes were insufficient to account for the increase in SSAT protein suggesting that translational regulation of SSAT must also occur. | N(1), N(12)-diethylspermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 7 | N1, N12-Bis(ethyl)spermine caused an increase in the SSAT half-life and a slight increase in SSAT mRNA, but these changes were insufficient to account for the increase in SSAT protein suggesting that translational regulation of SSAT must also occur. | N(1), N(12)-diethylspermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 8 | N1, N12-Bis(ethyl)spermine caused an increase in the SSAT half-life and a slight increase in SSAT mRNA, but these changes were insufficient to account for the increase in SSAT protein suggesting that translational regulation of SSAT must also occur. | N(1), N(12)-diethylspermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 9 | N1, N12-Bis(ethyl)spermine caused an increase in the SSAT half-life and a slight increase in SSAT mRNA, but these changes were insufficient to account for the increase in SSAT protein suggesting that translational regulation of SSAT must also occur. | N(1), N(12)-diethylspermine | diamine acetyltransferase 1 | Cricetulus griseus |