Title : Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease.

Pub. Date : 1999 Feb 16

PMID : 9990080






1 Functional Relationships(s)
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Protein Name
Organism
1 NPC1 levels in cultured fibroblasts were unchanged by incubation with low density lipoproteins or oxysterols but were increased 2- to 3-fold by the drugs progesterone and U-18666A, which block cholesterol transport out of lysosomes, and by the lysosomotropic agent NH4Cl. Progesterone NPC intracellular cholesterol transporter 1 Homo sapiens