Pub. Date : 1978 Apr
PMID : 99592
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PCDFs were about a thousand times more potent than PCBs (Kanechlor-500) as inducers of cytochrome P-450. | Dibenzofurans, Polychlorinated | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | Rats given 10 microgram/kg of PCDFs intraperitoneally for 3 days showed significantly increased hepatic cytochrome P-450 levels. | Dibenzofurans, Polychlorinated | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 3 | Following three daily doses of PCDFs (100 microgram/kg), cytochrome P-450 level and p-nitroanisole demethylase activity remained elevated for over 15 days, with a decrease to control levels after 30 days. | Dibenzofurans, Polychlorinated | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |