Title : [Effect of finasteride on the percentage of free PSA: implications in the early diagnosis of prostatic cancer].

Pub. Date : 1998 Nov-Dec

PMID : 9949572






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1 [Effect of finasteride on the percentage of free PSA: implications in the early diagnosis of prostatic cancer]. Finasteride aminopeptidase puromycin sensitive Homo sapiens
2 OBJECTIVE: To analyze the behaviour of free PSA percentage in finasteride-treated patients and to evaluate whether this ratio allows an increased PSA specificity in the early diagnosis of prostate cancer. Finasteride aminopeptidase puromycin sensitive Homo sapiens
3 RESULTS: Median PSA level in PBH patients was 1.6 ng/mL for the finasteride-treated group and 3.5 for the untreated group, p < 0.0001. Finasteride aminopeptidase puromycin sensitive Homo sapiens
4 CONCLUSION: Long-term treatment with finasteride reduces PSA serum concentration about 50% without changing the free PSA ratio. Finasteride aminopeptidase puromycin sensitive Homo sapiens
5 Free PSA ratio allows to increase PSA specificity and avoid unnecessary biopsied also in finasteride-treated patients. Finasteride aminopeptidase puromycin sensitive Homo sapiens
6 Free PSA ratio allows to increase PSA specificity and avoid unnecessary biopsied also in finasteride-treated patients. Finasteride aminopeptidase puromycin sensitive Homo sapiens