Title : Antipsychotic potential of CCK-based treatments: an assessment using the prepulse inhibition model of psychosis.

Pub. Date : 1999 Feb

PMID : 9885794






2 Functional Relationships(s)
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1 Subcutaneous (s.c.) injections of caerulein (10 micrograms/kg) a mixed CCKA/B agonist, partially reversed amphetamine-induced reduction of PPI; whereas, s.c. haloperidol (0.5 mg/kg) totally reversed amphetamine-induced disruption of PPI. Ceruletide cholecystokinin A receptor Homo sapiens
2 Caerulein"s effect on PPI was blocked by pretreatment with a CCKA antagonist (devazepide) but not a CCKB antagonist (L-365,260). Ceruletide cholecystokinin A receptor Homo sapiens