Title : Ability of bisbenzylputrescine and propanediamine analogs to modulate the intracellular polyamine pool of P388D1 cells.

Pub. Date : 1998 Dec

PMID : 9879934






1 Functional Relationships(s)
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1 The correlation between the cytotoxic results and the intracellular polyamine determination shows that the increase in spermine content along with the inhibition of retroconverting PAO enzyme increases the toxic effect of tested compounds (including spermine), suggesting that spermine toxicity is more important in the absence of intracellular oxidation processes. Polyamines polyamine oxidase (exo-N4-amino) Mus musculus