Pub. Date : 1999 Jan
PMID : 9858612
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclosporin A promotes translational silencing of autocrine interleukin-3 via ribosome-associated deadenylation. | Cyclosporine | interleukin 3 | Homo sapiens |
| 2 | Cyclosporin A (CsA), a calcineurin antagonist and blocker of interleukin-2 (IL-2) transcription in T cells, was found to inhibit translation of IL-3 mRNA in autocrine mast cell tumor lines. | Cyclosporine | interleukin 3 | Homo sapiens |
| 3 | Cyclosporin A (CsA), a calcineurin antagonist and blocker of interleukin-2 (IL-2) transcription in T cells, was found to inhibit translation of IL-3 mRNA in autocrine mast cell tumor lines. | Cyclosporine | interleukin 3 | Homo sapiens |
| 4 | The translational inhibition by CsA was specific to oncogenically induced lymphokines IL-3 and IL-4 but not to IL-6, c-jun, and c-myc, which are expressed in the nonmalignant precursor cells. | Cyclosporine | interleukin 3 | Homo sapiens |