Pub. Date : 1998 Nov 19
PMID : 9840921
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Administration of bcl-x-antisense oligonucleotides decreased Bcl-xL protein levels in the MKN-45 human gastric cancer cell line. | Oligonucleotides | BCL2 like 1 | Homo sapiens |
| 2 | Administration of bcl-x-antisense oligonucleotides decreased Bcl-xL protein levels in the MKN-45 human gastric cancer cell line. | Oligonucleotides | BCL2 like 1 | Homo sapiens |
| 3 | In conclusion, we demonstrated that administration of bcl-x-antisense oligonucleotides or overexpression of Bak protein induces sensitization to apoptosis in MKN-45 gastric cancer cells, suggesting that endogenous Bcl-xL expression in cancer cells is an important modulator of apoptosis. | Oligonucleotides | BCL2 like 1 | Homo sapiens |
| 4 | In conclusion, we demonstrated that administration of bcl-x-antisense oligonucleotides or overexpression of Bak protein induces sensitization to apoptosis in MKN-45 gastric cancer cells, suggesting that endogenous Bcl-xL expression in cancer cells is an important modulator of apoptosis. | Oligonucleotides | BCL2 like 1 | Homo sapiens |