Title : Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding.

Pub. Date : 1998 Dec 3

PMID : 9836624






3 Functional Relationships(s)
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1 Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding. Spiperone 5-hydroxytryptamine receptor 2A Rattus norvegicus
2 Spiperone (1) is a widely used pharmacological tool that acts as a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone 5-hydroxytryptamine receptor 2A Rattus norvegicus
3 As such, N1-alkyl analogues of spiperone may afford entry into a novel series of 5-HT2A-selective antagonists. Spiperone 5-hydroxytryptamine receptor 2A Rattus norvegicus