Title : Design and synthesis of a series of 6-substituted-2-pyridinylmethylamine derivatives as novel, high-affinity, selective agonists at 5-HT1A receptors.

Pub. Date : 1998 Dec 3

PMID : 9836623






2 Functional Relationships(s)
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1 SAR studies revealed that the pyridine nitrogen atom and the nature and the position of the substituents on the pyridine ring were critically involved in the ability of the compounds to recognize and activate 5-HT1A receptors. pyridine 5-hydroxytryptamine receptor 1A Homo sapiens
2 SAR studies revealed that the pyridine nitrogen atom and the nature and the position of the substituents on the pyridine ring were critically involved in the ability of the compounds to recognize and activate 5-HT1A receptors. pyridine 5-hydroxytryptamine receptor 1A Homo sapiens