Pub. Date : 1998 Nov-Dec
PMID : 9813392
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In view of the possible nutritional and toxicological implications of this inhibition, we decided to study the effect of Cu2+, Cd2+, Hg2+, Pb2+, and Mn2+ on Fe2+ and Fe3+ intestinal uptake. | ammonium ferrous sulfate | CD2 antigen | Mus musculus |
| 2 | It was found that Cd2+ and Cu2+, but not Hg2+, Mn2+, or Pb2+, significantly inhibited the uptake of Fe2+ (p < 0.001). | ammonium ferrous sulfate | CD2 antigen | Mus musculus |
| 3 | We propose either that Fe2+ and Fe3+ are transported through two different mechanisms, or that the enterocyte-mediated reduction of Fe3+, and the ensuing transport of Fe2+ are processes coupled in such a way that they are refractory to inhibition by Cu2+ and Cd2+. | ammonium ferrous sulfate | CD2 antigen | Mus musculus |