Title : Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells.

Pub. Date : 1998 Nov 20

PMID : 9813032






1 Functional Relationships(s)
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1 In parallel with ceramide generation, TNF-mediated inhibition of glucosylceramide and sphingomyelin (SM) synthase prevents the immediate metabolization of this lipid mediator. Glucosylceramides tumor necrosis factor Homo sapiens