Title : Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretion.

Pub. Date : 1998 Nov

PMID : 9798935






1 Functional Relationships(s)
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1 These conclusions are supported by the following findings: (a) Only partial blockade of APPs secretion is observed when PKC, p21ras, or MAPK is fully inhibited by their respective specific inhibitors, GF109203X, S-trans, trans-farnesylthiosalicylic acid, and PD98059. farnesylthiosalicylic acid HRas proto-oncogene, GTPase Rattus norvegicus