Title : Inactivation of papain by antithrombin due to autolytic digestion: a model of serpin inactivation of cysteine proteinases.

Pub. Date : 1998 Nov 1

PMID : 9794814






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 An antithrombin to papain inactivation stoichiometry of approximately 3 indicated extensive cleavage of the inhibitor concurrent with enzyme inactivation, a behaviour verified by SDS/PAGE. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens
2 The papain band in SDS/PAGE progressively disappeared on reaction of the enzyme with increasing amounts of antithrombin, but no band representing a stable antithrombin-papain complex appeared. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens