Title : Dexamethasone but not indomethacin inhibits human phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity by down-regulating expression of genes encoding oxidase components.

Pub. Date : 1998 Nov 1

PMID : 9794432






1 Functional Relationships(s)
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1 Dexamethasone down-regulated the NADPH oxidase system of cytokine-differentiated THP-1 cells as assessed by an inhibition on the PMA-stimulated superoxide release, cytochrome b558 content, and expression of the gp91-phox and p47-phox genes. Tetradecanoylphorbol Acetate neutrophil cytosolic factor 1 Homo sapiens