Pub. Date : 1998 Aug-Sep
PMID : 9792441
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Expression of CD95 (Apo-1/Fas) ligand and its two receptor isoforms, in response to all-trans retinoic acid and interferon gamma (IFNgamma), was analyzed atthe mRNA and protein levels in human Tera-2 embryonal carcinoma cells. | Tretinoin | Fas cell surface death receptor | Homo sapiens |
2 | Expression of CD95 (Apo-1/Fas) ligand and its two receptor isoforms, in response to all-trans retinoic acid and interferon gamma (IFNgamma), was analyzed atthe mRNA and protein levels in human Tera-2 embryonal carcinoma cells. | Tretinoin | Fas cell surface death receptor | Homo sapiens |
3 | Exposure of Tera-2 cells to all-trans retinoic acid for up to 16 days led to a decrease of CD95 ligand expression when compared to the control conditions, whereas expression of both CD95 isoforms increased. | Tretinoin | Fas cell surface death receptor | Homo sapiens |
4 | Exposure of Tera-2 cells to all-trans retinoic acid for up to 16 days led to a decrease of CD95 ligand expression when compared to the control conditions, whereas expression of both CD95 isoforms increased. | Tretinoin | Fas cell surface death receptor | Homo sapiens |
5 | These changes were functionally significant since Tera-2 cells treated with all-trans retinoic acid for six to 16 days were more susceptible to CD95-mediated apoptosis. | Tretinoin | Fas cell surface death receptor | Homo sapiens |