Title : Effect of forskolin on endothelin-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells.

Pub. Date : 1998 Aug

PMID : 9788291






3 Functional Relationships(s)
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1 While after treatment with forskolin for 24 h, the cells retained the ability to respond to ET-1-induced Ca2+ mobilization to the same extent as the control group. Colforsin endothelin 1 Canis lupus familiaris
2 Forskolin (1-100 microM) inhibited the ET-1-induced increase in [Ca2+]i, but the lower concentrations had little effect on this response. Colforsin endothelin 1 Canis lupus familiaris
3 The water-soluble forskolin analogue L-858051, 7-deacetyl-7beta-(gamma-N-methylpiperazino)-butyryl forskolin, significantly inhibited ET-1-stimulated IPs accumulation. Colforsin endothelin 1 Canis lupus familiaris