Title : Effect of pirenzepine on gastric endocrine cell kinetics during lansoprazole administration.

Pub. Date : 1998 Oct

PMID : 9773926






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the group on the lansoprazole and pirenzepine combination, serum gastrin levels decreased, and gastrin and enterochromaffin-like cell numbers were significantly decreased, compared with the respective variables in the group on lansoprazole alone, while the number of somatostatin cells increased in the group on the combination. Pirenzepine gastrin Rattus norvegicus
2 In the group on the lansoprazole and pirenzepine combination, serum gastrin levels decreased, and gastrin and enterochromaffin-like cell numbers were significantly decreased, compared with the respective variables in the group on lansoprazole alone, while the number of somatostatin cells increased in the group on the combination. Pirenzepine gastrin Rattus norvegicus
3 It was thus demonstrated that pirenzepine corrects the abnormal gastric secretion kinetics resulting from treatment with lansoprazole alone, such as hypergastrinemia and gastrin and enterochromaffin-like cell hyperplasia. Pirenzepine gastrin Rattus norvegicus