Title : Effects of chronic exposure to PCBs on cytochrome P450 systems and steroidogenesis in liver and testis of bulls (Bos taurus).

Pub. Date : 1998 May

PMID : 9773499






3 Functional Relationships(s)
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Protein Name
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1 A high level of PCB-inducible androstenedione formation was also found. Androstenedione pyruvate carboxylase Bos taurus
2 The testicular microsomal CYP activities were non-specifically reduced by the PCB exposure, except for the androstenedione formation and 16 beta-hydroxylation of testosterone. Androstenedione pyruvate carboxylase Bos taurus
3 The latter activity as well as the hepatic testosterone 6 beta-hydroxylation and hepatic and testicular androstenedione formation may significantly contribute to the decrease in testosterone levels after the PCB intake. Androstenedione pyruvate carboxylase Bos taurus