Title : Wortmannin blocks Yersinia invasin-triggered internalization, but not interleukin-8 production by epithelial cells.

Pub. Date : 1998 Jun

PMID : 9749983






1 Functional Relationships(s)
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1 While staurosporin and genistein inhibited both Yersinia invasion and Yersinia-triggered IL-8 secretion, wortmannin, an inhibitor of the phosphatidylinositol-3-phosphate kinase (PI3-K), blocked invasion of Y. enterocolitica into HeLa cells but did not show any effect on IL-8 secretion. Genistein C-X-C motif chemokine ligand 8 Homo sapiens