Title : Cell surface proteoglycans are necessary for A27L protein-mediated cell fusion: identification of the N-terminal region of A27L protein as the glycosaminoglycan-binding domain.

Pub. Date : 1998 Oct

PMID : 9733888






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When we investigated whether cell surface GAGs also participate in A27L-dependent fusion, our results indicated that soluble A27L protein blocked cell fusion, whereas D-A27L protein did not. Glycosaminoglycans IMV surface protein Vaccinia virus
2 When we investigated whether cell surface GAGs also participate in A27L-dependent fusion, our results indicated that soluble A27L protein blocked cell fusion, whereas D-A27L protein did not. Glycosaminoglycans IMV surface protein Vaccinia virus
3 When we investigated whether cell surface GAGs also participate in A27L-dependent fusion, our results indicated that soluble A27L protein blocked cell fusion, whereas D-A27L protein did not. Glycosaminoglycans IMV surface protein Vaccinia virus
4 Taken together, the results therefore demonstrated that A27L-mediated cell fusion is triggered by its interaction with cell surface GAGs through the N-terminal domain. Glycosaminoglycans IMV surface protein Vaccinia virus