Title : Control of AMP deaminase 1 binding to myosin heavy chain.

Pub. Date : 1998 Sep

PMID : 9730972






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A nucleotide binding site, which is located at residues 660-674, controls binding of AMPD1 to MHC in response to changes in intracellular ATP concentration. Adenosine Triphosphate major histocompatibility complex, class I, C Homo sapiens
2 Deletion analyses demonstrate that the amino-terminal 65 residues of AMPD1 play a critical role in modulating the sensitivity to ATP-induced inhibition of MHC binding. Adenosine Triphosphate major histocompatibility complex, class I, C Homo sapiens
3 Alternative splicing of the AMPD1 gene product, which alters the sequence of residues 8-12, produces two AMPD1 isoforms that exhibit different MHC binding properties in the presence of ATP. Adenosine Triphosphate major histocompatibility complex, class I, C Homo sapiens