Pub. Date : 1998 Sep
PMID : 9730972
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A nucleotide binding site, which is located at residues 660-674, controls binding of AMPD1 to MHC in response to changes in intracellular ATP concentration. | Adenosine Triphosphate | major histocompatibility complex, class I, C | Homo sapiens |
2 | Deletion analyses demonstrate that the amino-terminal 65 residues of AMPD1 play a critical role in modulating the sensitivity to ATP-induced inhibition of MHC binding. | Adenosine Triphosphate | major histocompatibility complex, class I, C | Homo sapiens |
3 | Alternative splicing of the AMPD1 gene product, which alters the sequence of residues 8-12, produces two AMPD1 isoforms that exhibit different MHC binding properties in the presence of ATP. | Adenosine Triphosphate | major histocompatibility complex, class I, C | Homo sapiens |