Title : Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.

Pub. Date : 1998 Sep 8

PMID : 9730840






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 To evaluate the influence of the cyclization, this Gln was chemically converted into pGlu in both MCP-2 variants. Pyrrolidonecarboxylic Acid C-C motif chemokine ligand 8 Homo sapiens
2 However, for both MCP-2 variants the NH2-terminal pyroglutamate was shown to be essential for chemotaxis, but not for calcium mobilization. Pyrrolidonecarboxylic Acid C-C motif chemokine ligand 8 Homo sapiens