Title : Dual regulatory effects of interferon-alpha, -beta, and -gamma on interleukin-8 gene expression by human gingival fibroblasts in culture upon stimulation with lipopolysaccharide from Prevotella intermedia, interleukin-1alpha, or tumor necrosis factor-alpha.

Pub. Date : 1998 Aug

PMID : 9719033






1 Functional Relationships(s)
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1 The IL-8 mRNA accumulation in response to P. intermedia LPS was inhibited by tosylphenyl-alanyl chloromethyl-ketone, an inhibitor of NF-kappaB activation, although the NF-kappaB activation itself was not altered by IFN-gamma. Tosylphenylalanyl Chloromethyl Ketone C-X-C motif chemokine ligand 8 Homo sapiens