Title : Intracellular nucleotide-mediated gating of SUR/Kir6.0 complex potassium channels expressed in a mammalian cell line and its modification by pinacidil.

Pub. Date : 1998 Sep 15

PMID : 9714850






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The potency of adenine, guanine or uracil nucleotides to activate SUR2B/Kir6.1 channels was enhanced by pinacidil. Guanine potassium inwardly rectifying channel subfamily J member 8 Homo sapiens
2 In the presence of pinacidil, adenine and guanine, but not uracil, nucleotides exhibited bell-shaped concentration-dependent activating effects on SUR2B/Kir6.1 channels. Guanine potassium inwardly rectifying channel subfamily J member 8 Homo sapiens