Title : Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways.

Pub. Date : 1998 Aug 15

PMID : 9712041






1 Functional Relationships(s)
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1 Granulysin- and ceramide-induced apoptosis are similar in that they both are only minimally inhibited by the more selective cysteine protease p32 (caspase 3)-like caspase inhibitor N-acetyl-Asp-Glu-Val-Asp aldehyde, while they are significantly inhibited by the more general caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone (Z-VAD-fmk). Ceramides inhibitor of growth family member 2 Homo sapiens