Pub. Date : 1998 Aug
PMID : 9698292
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Of the recombinant P450 isoforms tested, only CYP2B6 and CYP2C9 formed nirvanol from (S)-MP. | ethylphenylhydantoin | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Therefore, the N-demethylation of (S)-MP to nirvanol may be a useful means of probing the activity of CYP2B6 in vitro when concentrations of >1000 microM are used, but it is unlikely to be a suitable phenotyping tool for this isoform in vivo, where concentrations of >1000 microM are rarely encountered. | ethylphenylhydantoin | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |