Title : Divergence of the feeding and thermogenic pathways influenced by NPY in the hypothalamic PVN of the rat.

Pub. Date : 1998 Aug

PMID : 9688682






4 Functional Relationships(s)
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1 Previously we reported that the feeding and BAT effects induced by NPY in the PVN are blocked by 50 microg naltrexone (NTX) in the rostral nucleus of the solitary tract (rNTS). Naltrexone neuropeptide Y Rattus norvegicus
2 Previously we reported that the feeding and BAT effects induced by NPY in the PVN are blocked by 50 microg naltrexone (NTX) in the rostral nucleus of the solitary tract (rNTS). Naltrexone neuropeptide Y Rattus norvegicus
3 We sought to determine whether the effect of rNTS NTX on PVN NPY-induced alterations in energy metabolism occurred at lower doses of NTX. Naltrexone neuropeptide Y Rattus norvegicus
4 One-hour feeding response to PVN NPY was significantly and dose dependently decreased by 10 and 25 microg rNTS NTX (-23 and -31%, respectively). Naltrexone neuropeptide Y Rattus norvegicus