Title : Differential effects of bupivacaine on cardiac K channels: role of channel inactivation and subunit composition in drug-channel interaction.

Pub. Date : 1998 Jul

PMID : 9684721






1 Functional Relationships(s)
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1 With hKvLQT1 co-expressed with hIsK, bupivacaine bound preferentially at negative voltages when channels were in the closed state, and unbound at depolarized voltages when channels opened. Bupivacaine potassium voltage-gated channel subfamily Q member 1 Homo sapiens