Title : Effect of reactive oxygen species on iron regulatory protein activity.

Pub. Date : 1998 Jun 30

PMID : 9668619






3 Functional Relationships(s)
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1 Although iron is the main regulator of IRP activity, IRP is also influenced by other factors, including the redox state. Iron Wnt family member 2 Homo sapiens
2 Conceivably, downregulation of IRP activity by O2 and H2O2 may facilitate iron sequestration into ferritin, thus limiting the pro-oxidant challenge of iron. Iron Wnt family member 2 Homo sapiens
3 Conceivably, downregulation of IRP activity by O2 and H2O2 may facilitate iron sequestration into ferritin, thus limiting the pro-oxidant challenge of iron. Iron Wnt family member 2 Homo sapiens