Title : A new photoactivatable reagent capable of transferring a radiolabel to target proteins. Application to the human growth hormone-rat liver prolactin receptor interaction.

Pub. Date : 1998 Jul-Aug

PMID : 9667953






1 Functional Relationships(s)
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1 Upon partial reduction of human growth hormone (hGH) with dithiothreitol, its C-terminal disulfide bond between residues 182 and 189 was cleaved and the nascent thiol groups were modified with [125I]ASDPE to yield [125I]ASET-hGH [1-(thio-hGH)-2-(3"-[125I]iodo-5"-azidosalicylamido)ethane]. Disulfides growth hormone 1 Homo sapiens