Title : Use of c-Src and c-Fos knockout mice for the studies on the role of c-Src kinase signaling in the expression of toxicity of TCDD.

Pub. Date : 1998

PMID : 9664232






2 Functional Relationships(s)
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1 Use of c-Src and c-Fos knockout mice for the studies on the role of c-Src kinase signaling in the expression of toxicity of TCDD. Polychlorinated Dibenzodioxins c-src tyrosine kinase Mus musculus
2 First, we could show that chemical inhibition of c-src kinase could produce practically the same phenomenon of reduced toxicity of TCDD in wild-type mice cotreated with geldanamycin, a specific chemical inhibitor known to suppress c-src kinase. Polychlorinated Dibenzodioxins c-src tyrosine kinase Mus musculus